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United StatesHealthcare and life sciences2022 – ongoing

Tempus AI

SmartPath-assisted tissue preparation for molecular sequencing

Tempus reported 25% more DNA yields within its target range in a SmartPath validation trial

WorkingCompany's own claim

Problem

Pathologists estimated how much tissue to extract for sequencing. Incorrect estimates could waste tissue or require another extraction.

Approach

Tempus developed SmartPath to identify tumor regions in digitized slides and predict DNA yield. It recommended extraction areas and slide counts for pathologists. An internal laboratory trial compared assisted review with traditional review across 501 clinical colorectal cancer slides.

Results

25%more DNA yields within the target range with assisted review than with traditional review, per Tempus researchersCompany's own claim[1]

Takeaway

The measured result concerned tissue preparation in an internal trial. It did not establish a reduction in total laboratory costs.

Categories

Business function
Production and quality
Innovation type
Process innovation
Evidence
Company's own claim

Sources

Source summaries

[1]arXiv26 Mar 2022

Tempus researchers described SmartPath and an internal laboratory validation. The assisted group produced 25% more DNA yields within the specified range than the traditional-review group.

Full details are in the original sources.

Added 1 Nov 2026 · Updated 1 Nov 2026
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