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United StatesHealthcare and life sciences2019 – ongoing

Johns Hopkins Health System

TREWS early warning for sepsis

Johns Hopkins reported that TREWS identified more than 80% of patients with sepsis before onset

WorkingCompany's own claimOfficial ↗

Problem

Early sepsis was difficult to diagnose because its symptoms overlapped with other illnesses. Existing alert criteria produced frequent false warnings.

Approach

Johns Hopkins computer scientist Suchi Saria and colleagues developed TREWS to assess patient-record data for sepsis risk. The system alerted clinicians through electronic health records and prompted clinical responses. It was operating at Howard County General Hospital and Suburban Hospital by June 2019.

Results

more than 80%of patients with sepsis identified before onset, according to researcher Katharine HenryCompany's own claim[1]

Takeaway

TREWS delivered warnings within clinicians' existing records. Its reported detection rate did not by itself measure an improvement in patient survival.

Categories

Business function
Production and quality
Innovation type
Process innovation
Evidence
Company's own claim

Sources

  1. Early-Warning Algorithm Targeting Sepsis Deployed at Johns Hopkins
    Johns Hopkins Medicine7 Jun 2019Company publication

Source summaries

[1]Johns Hopkins Medicine7 Jun 2019

Johns Hopkins described TREWS operating at 2 hospitals and planned expansion to other facilities. A researcher reported that it detected more than 80% of patients with sepsis before onset.

Full details are in the original sources.

Added 1 Nov 2026 · Updated 1 Nov 2026
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