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United StatesHealthcare and life sciences2025 – ongoing

Myriad Genetics

Image Genius: generative AI document classification for prior authorization

Myriad Genetics cut document classification cost by 77% after moving from Textract and Comprehend to Nova models on Amazon Bedrock

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Problem

Myriad Genetics handles thousands of medical documents a day to support prior authorization. Its first classification system, built on Amazon Textract and Amazon Comprehend, cost about 3 cents a page and took 8.5 minutes per document. Staff extracted key data from forms by hand because the layouts varied.

Approach

Myriad and AWS rebuilt the pipeline on the open-source GenAI Intelligent Document Processing Accelerator. Amazon Nova Pro classified documents, with prompts refined from document samples and negative examples. Amazon Nova Premier extracted data, including checkboxes. The output went into Myriad's authorization system through an event-driven pipeline.

Results

98%classification accuracy, up from 94%, per AWS and Myriad authorsVendor case study[1]
77%reduction in processing cost, per AWS and Myriad authorsVendor case study[1]
1.5 minutesclassification time per document, down from 8.5 minutes, per AWS and Myriad authorsVendor case study[1]

Takeaway

The first build proved the use case but was too costly to keep. Switching to a cheaper model and tuning the prompts changed the cost per page.

Categories

Business function
Production and quality
Innovation type
Process innovation
AI technology
Generative AI
Evidence
Vendor case study

Sources

Source summaries

[1]AWS Machine Learning Blog26 Nov 2025

AWS and two Myriad engineers describe moving document classification and extraction from Textract and Comprehend to Bedrock with Nova models. They report accuracy of 98% against 94% before, a 77% cost cut and classification time of 1.5 minutes against 8.5. The post does not describe its measurement method in full.

Full details are in the original sources.

Added 2 Nov 2026 · Updated 2 Nov 2026
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