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United StatesHealthcare and life sciences2019 – ongoing

Michigan Medicine

Epic Sepsis Model alerts

Michigan Medicine paused Epic sepsis alerts after nurses reported excessive alerts during COVID-19

Scaled backIndependent study

Problem

Michigan Medicine used automated sepsis warnings to help clinicians identify patients who might need treatment. The model calculated risk from information in the electronic health record.

Approach

Epic Sepsis Model alerts began on two hospital units in March 2019 and expanded to a third in August. In April 2020, Michigan paused the alerts after nurses reported excessive alerting during the first COVID-19 wave. A subsequent multicenter study linked the pause to rising alert volume, while explicitly stating that it had not evaluated alert accuracy. A separate account by clinical AI researchers, including the chair of Michigan's AI governance committee, described the deactivation as a response to changes in the patient population and the relationship between fever and bacterial sepsis.

Results

2hospital units where model alerts first went live in March 2019Independent study[2]

Takeaway

Nursing reports exposed a change in the model's operational burden. Michigan's governance committee could disable the alerts when the patient population changed.

Categories

Business function
Production and quality
Innovation type
Process innovation
Evidence
Independent study

Sources

  1. The Clinician and Dataset Shift in Artificial Intelligence
    The New England Journal of Medicine15 Jul 2021Research paper or report

Source summaries

[1]JAMA Network Open19 Nov 2021

The authors documented Michigan's April 2020 pause after nursing reports of excessive alerts. Their multicenter analysis measured alert volume rather than diagnostic accuracy and discussed how COVID-19 changed the demands placed on sepsis workflows.

[2]JAMA Internal Medicine21 Jun 2021

The study described the model's use of electronic health record data and Michigan's deployment dates. Alerts started on two units on March 11, 2019, and expanded to a third on August 12, 2019.

[3]The New England Journal of Medicine15 Jul 2021

The authors described Michigan's deactivation of Epic's sepsis model during COVID-19 as a response to dataset shift. They reported that the hospital's clinical AI governance committee decommissioned its use after spurious alerting.

Full details are in the original sources.

Added 4 Nov 2026 · Updated 4 Nov 2026
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